A case of pan-resistant Burkholderia cepacia complex bacteremic pneumonia, after lung transplantation treated with a targeted combination therapy. Cantón-Bulnes María Luisa,Hurtado Martínez Ángela,López-Cerero Lorena,Arenzana Seisdedos Ángel,Merino-Bohorquez Vicente,Garnacho-Montero José Transplant infectious disease : an official journal of the Transplantation Society We describe a case of one patient with cystic fibrosis who developed a pan-resistant Burkholderia cepacia complex rapidly progressive bacteraemic pneunonia, following bilateral lung transplantation. The patient was treated with a targeted combination antibiotic therapy (meropenem plus ceftazidime/avibactam plus high doses of nebulized colistimethate sodium). Evolution of the disease was complicated by multiple organ system dysfunction. Finally, clinical improvement and microbiological cure was achieved. 10.1111/tid.13034